Wal-yan Respiratory Research Centre
Team
P4 Respiratory Health for Kids projects
Reports and Findings
Azithromycin reduces bronchial wall thickening in infants with cystic fibrosis
COMBAT-CF showed that children aged 0-3 years treated with azithromycin did clinically better than placebo but there was no effect on CT-scores. We reanalysed CTs using an automatic bronchus-artery (BA) analysis.
Cystic Fibrosis Published research Early Childhood Development P4 Respiratory Health for Kids Subsite: WalyanLower infant mortality, higher household size, and more access to contraception reduce fertility in low- and middle-income nations
Although average contraceptive use has increased globally in recent decades, an estimated 222 million (26%) of women of child-bearing age worldwide face an unmet need for family planning-defined as a discrepancy between fertility preferences and contraception practice, or failing to translate desires to avoid pregnancy into preventative behaviours and practices.
Published research P4 Respiratory Health for Kids Subsite: WalyanNet benefit of smaller human populations to environmental integrity and individual health and wellbeing
The global human population is still growing such that our collective enterprise is driving environmental catastrophe. Despite a decline in average population growth rate, we are still experiencing the highest annual increase of global human population size in the history of our species-averaging an additional 84 million people per year since 1990.
Published research P4 Respiratory Health for Kids Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Subsite: Walyan Infectious Disease Ecology and Modelling Climate changeA phase I clinical trial assessing the safety, tolerability, and pharmacokinetics of inhaled ethanol in humans as a potential treatment for respiratory tract infections
Current treatments for respiratory infections are severely limited. Ethanol's unique properties including antimicrobial, immunomodulatory, and surfactant-like activity make it a promising candidate treatment for respiratory infections if it can be delivered safely to the airway by inhalation. Here, we explore the safety, tolerability, and pharmacokinetics of inhaled ethanol in a phase I clinical trial.
Published research Infectious Diseases P4 Respiratory Health for Kids Subsite: Walyan BREATH Respiratory viral infections