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        News & Events

        'Natural killers' potential new cancer weapon

        The Cancer Immunology team at Telethon Kids is investigating how the body's 'natural killer' cells can be harnessed to fight cancer – whilst also protecting kids from nasty chemotherapy side effects. ...

        News & Events

        NHMRC funding boost to child health research

        Telethon Kids researchers will use nearly $8.5 million awarded by the National Health and Medical Research Council (NHMRC) to tackle health issues including respiratory disease, brain cancer, vaccination and Aboriginal health. ...

        News & Events

        Replication of rare aggressive brain cancer could pave the way for better treatments

        In an Australian-first, Telethon Kids Institute researchers have developed a new tool that could improve outcomes for children with a highly aggressive type of brain cancer. ...

        News & Events

        Experts Pledge Global Assault on Kids’ Cancer

        A global plan to tackle one of the most aggressive types of childhood brain tumours will be developed as a result of a meeting of international experts in WA. ...

        News & Events

        New imaging equipment to boost children's cancer research

        A cutting edge cancer imaging facility will help specialist children's cancer researchers at Perth's Telethon Institute for Child Health Research. ...

        News & Events

        Researchers narrow down field of new treatments for most common childhood brain cancer

        Cancer researchers have narrowed-down the field of immunotherapy drugs which could be used to tackle a form of childhood brain cancer. ...

        News & Events

        Lab results confirm promise of new immunotherapy gel for kids cancer

        Newly published research from Telethon Kids Institute and The University of Western Australia has found a gel applied during surgery to treat sarcoma tumours is both safe and highly effective at preventing the cancer from growing back. ...

        News & Events

        Telethon Kids researchers awarded Raine Medical Research Foundation funding

        Congratulations to three Telethon Kids Institute researchers, who have been awarded funding from the Raine Medical Research Foundation. ...

        Research

        Long-term outcomes of symptomatic optic pathway glioma: 32-year experience at a single Western Australian tertiary pediatric oncology center

        Optic pathway gliomas (OPGs) are associated with significant risk of visual and endocrine morbidity, but data on long-term outcomes in symptomatic patients is sparse. This study reviews the clinical course, disease progression, survival outcomes and long-term sequelae in pediatric patients with symptomatic OPGs in our institution over three decades. ...

        Research

        Reproducible Bioinformatics Analysis Workflows for Detecting IGH Gene Fusions in B-Cell Acute Lymphoblastic Leukaemia Patients

        B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by diverse genomic alterations, the most frequent being gene fusions detected via transcriptomic analysis (mRNA-seq). Due to its hypervariable nature, gene fusions involving the Immunoglobulin Heavy Chain (IGH) locus can be difficult to detect with standard gene fusion calling algorithms and significant computational resources and analysis times are required. We aimed to optimize a gene fusion calling workflow to achieve best-case sensitivity for IGH gene fusion detection. ...

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