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        Vitamin D C3-epimer levels are proportionally higher with oral vitamin D supplementation compared to ultraviolet irradiation of skin in mice but not humans

        The proportion of 25(OH)D3 that undergoes epimerization is greater with oral vitamin D3 supplementation than exposure to UVR in mice, but not in humans ...

        Research

        Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice

        Skin exposure to ultraviolet radiation alters the faecal microbiome, and further investigations to explore the implications of this in health and disease are warranted ...

        Research

        Prevalence and predictors of vitamin D deficiency in a nationally representative sample of Australian adolescents and young adults

        Vitamin D deficiency is a public health concern worldwide. Maintaining vitamin D sufficiency during growth periods is essential. We aimed to determine the prevalence and predictors of vitamin D deficiency in Australian adolescents and young adults. ...

        Research

        Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions

        Although genetic and epidemiological evidence indicates vitamin D insufficiency contributes to multiple sclerosis (MS), and serum levels of vitamin D increase on treatment with cholecalciferol, recent metanalyses indicate that this vitamin D form does not ameliorate disease. Genetic variation in genes regulating vitamin D, and regulated by vitamin D, affect MS risk. ...

        Research

        Sun-immune connection

        Exposure to ultraviolet radiation damages skin cell DNA but skin cancers develop because ultraviolet radiation also affects the immune system ...

        Research

        Maternal vitamin D deficiency alters fetal brain development in the BALB/c mouse.

        Prenatal exposure to vitamin D is thought to be critical for optimal fetal neurodevelopment, yet vitamin D deficiency is apparent in a growing proportion of... ...

        Research

        Comparing the effects of sun exposure and vitamin D supplementation on vitamin D insufficiency, and immune and cardio-metabolic function

        Adults living in the sunny Australian climate are at high risk of skin cancer, but vitamin D deficiency (defined here as a serum 25-hydroxyvitamin D... ...

        Research

        Modulation of the immune system by UV radiation: More than just the effects of vitamin D?

        Humans obtain most of their vitamin D through the exposure of skin to sunlight ...

        Research

        Immune mechanisms by which topically applied vitamin D acts as a therapeutic agent

        Vitamin D, nutrition, diet, therapeutic agent ...

        Research

        Randomised controlled trial analysing supplementation with 250 versus 500 units of vitamin D3,

        The rate of non-compliance with vitamin D supplementation is as high as 45%. This is why randomised controlled trials are needed to analyse the response... ...

        Research

        Pterygium and conjunctival ultraviolet autofluorescence in young Australian adults: The Raine study

        Sun exposure is associated with several ophthalmic diseases, including pterygium which may develop in adolescence. ...

        Research

        Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D

        UVR or sunlight exposure may be an effective means of suppressing the development of obesity and MetS, through mechanisms that are independent of vitamin D ...

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