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Reports and Findings
Protocol for delivery of intraoperative immunotherapy to mice by surgical debulking of subcutaneous tumors
Pre-clinical studies developing novel therapies to prevent cancer recurrence require appropriate surgical models. Here, we present a protocol for surgical debulking of subcutaneous tumors in mice, which allows for intraoperative application of immunotherapy-loaded biomaterials.
Children's Cancers Published research Sarcoma Translational ResearchFinancial toxicity of informal caregivers of colorectal cancer patients: A cross-sectional study
To assess the level of financial toxicity of informal caregivers of colorectal cancer patients and explore the related key influencing factors.
Published research Sarcoma Translational Research Cancers (other)Supportive care needs and associated factors among caregivers of patients with colorectal cancer: a cross-sectional study
To assess the level of supportive care needs of caregivers of colorectal cancer patients and explore the related key influencing factors. Totaling 283 caregivers of patients with colorectal cancer were investigated in this study.
Published research Sarcoma Translational Research Cancers (other)Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner
Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens has improved response rates and increased survival in some cancers. However, most patients do not respond to treatment and immune checkpoint therapy can cause severe side effects. Therefore, there is a need for alternative immunomodulatory drugs that enhance chemotherapy.
Children's Cancers Published research Subsite: Cancer Sarcoma Translational Research