Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• May 2011

Pseudomonas aeruginosa is an opportunistic pathogen. Here, we report the isolation of four bacteriophages from wastewater. All four bacteriophages belong to the Myoviridae family. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

These findings indicate that early CF lung disease is characterized by an increased mucus burden and inflammatory markers without infection or structural lung disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

A better understanding of the innate immune responses by CF airway epithelial cells is needed to identify why viral infections are more severe in CF ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

The method outlined in this article is a customization of the whole exhaust exposure method generated by Mullins et al. (2016) using reprogrammed primary human airway epithelial cells as described by Martinovich et al. (2017). It has been used successfully to generate recently published data (Landwehr et al. 2021). The goal was to generate an exhaust exposure model where exhaust is collected from a modern engine, real-world exhaust concentrations are used and relevant tissues exposed to assess the effects of multiple biodiesel exposures. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Pulmonary inflammation in surveillance bronchoalveolar lavage has a cumulative effect on structural lung disease extent, more so than infection ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

Our data illustrate that rhinovirus infection is capable of infecting upper and lower airway epithelial cells, driving cell death and inflammation ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

Stephen Yuliya Stick Karpievitch SM YK MB BChir PhD MRCP FRACP PhD, MS, BS Head, P4 Respiratory Health for Kids Ai and Data Analytics Lead, Respiratory Research +61863191356 yuliya.karpievitch@telethonkids.org.au Head, P4 Respiratory Health for Kids ...

• 1. Telethon Kids Institute
• Our research
• Chronic and Severe Diseases
• Respiratory Health Program
• P4 Respiratory Health for Kids

Respiratory disease in cattle is a significant global concern, yet current diagnostic methods are limited, and there is a lack of crush-side tests for detecting active disease. To address this gap, we propose utilizing electrical impedance tomography (EIT), a non-invasive imaging technique that provides real-time visualization of lung ventilation dynamics. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

A significant proportion of chronic obstructive pulmonary disease exacerbations are strongly associated with rhinovirus infection (HRV). In this study, we combined long-term cigarette smoke exposure with HRV infection in a mouse model. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Understanding early triggers of Cystic Fibrosis Lung Disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• October 2016

Modulation of ASL pH has been proposed as a therapy for CF. However, evidence that ASL pH is reduced in CF is limited and conflicting. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017